Chlormethiazole--no hangover effect but not an ideal hypnotic for the young.

نویسندگان

  • C M Castleden
  • C F George
  • E M Sedgwick
چکیده

The hangover effects of 768 mg chlormethiazole, an hypnotic with a half-life of approximately 4 hr, were compared with those of placebo in a double-blind cross-over study in 8 young subjects. Ten hours after dosing there were no differences between the preparations in the subjects' psychomotor performance, EEG sleep scores, or visual analogue ratings. Thus, an hypnotic which is rapidly removed from the body may confer considerable advantages. However, all 8 subjects had unpleasant nasal symptoms following chlormethiazole, and it is therefore not an ideal hypnotic for this age group.

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عنوان ژورنال:
  • Postgraduate medical journal

دوره 55 641  شماره 

صفحات  -

تاریخ انتشار 1979